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pentobarbital will lower the level or result of tamoxifen by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Observe.pentobarbital will lower the extent or impact of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with potent CYP3A4 inducers is just not suggestedpentobarbital will l